Enabling Circuits for Smart and Connected Medical Devices

Principal Investigator
Project Description

Professor Hall is developing ultra-low power circuits and sensors for future IoT biosensors. These BioMote sensors are the size of a single grain of rice and will be subcutaneously injected through a 16-gauge needle into interstitial fluid (ISF), the quasi-stationary extracellular fluid surrounding cells composed of nutrients, metabolites, and waste. ISF is highly correlated with blood enabling continuous, long-term biomarker monitoring. The batteryless device will be wirelessly powered through an inductive link that will also be used for bi-directional communication. Electrochemical biosensors will be incorporated on the BioMote to enable long-term, continuous biomarker measurements. Enzymes immobilized on the surface will provide specificity (i.e., glucose, lactate, alcohol, or other disease specific biomarkers.) The measured data will be sent back to a wearable device (smartwatch or other data aggregator) for further processing. It is believed that such a device would truly unlock the potential for long-term, medically relevant wearable biosensors and fundamentally change how we monitor and track disease.